Cholera toxin induces maturation of human dendritic cells and licences them for Th2 priming

WEGENER’S AUTOANTIGEN INDUCES MATURATION OF DENDRITIC CELLS AND LICENCES THEM FOR TH1 PRIMING VIA THE PROTEASE-ACTIVATED RECEPTOR-2 PATHWAY Running head: Maturation of dendritic cells by proteinase 3

WEGENER’S AUTOANTIGEN INDUCES MATURATION OF DENDRITIC CELLS AND LICENCES THEM FOR TH1 PRIMING VIA THE PROTEASE-ACTIVATED RECEPTOR-2 PATHWAY Running head: Maturation of dendritic cells by proteinase 3 Elena Csernok, MaiXing Ai, Wolfgang L Gross, Daniel Wicklein*, Arnd Petersen*, Buko Lindner** , Peter Lamprecht, Julia U Holle, Bernhard Hellmich Department of Rheumatology, University-Hospital of ...

Monocyte-Derived Dendritic Cells by Collagen Induces Maturation of Human

Monocyte-Derived Dendritic Cells Galectin-9 Induces Maturation of Human

[Galectin-9 induces maturation of human monocyte-derived dendritic cells].

We investigated the role of galectin-9 (Gal-9) in maturation of dendritic cells (DC). Culture of immature DCs with exogenous Gal-9 markedly increased the surface expression of CD40, CD54, CD80, CD83, CD86, and HLA-DR in a concentration-dependent manner, although Gal-9 had no effect on differentiation of human monocytes into immature DCs. Gal-9-treated DCs secreted IL-12 but not IL-10, and they ...

Immunomodulatory Effects of Mice Mesenchymal Stem Cells on Maturation and Activation of Dendritic Cells

Background: Mesenchymal stem cells (MSCs) possess a wide range of immunomodulatory functions mostly in immune cells including dendritic cells (DCs). DCs are the key cells in the immune response and play an important role in initiating cell-mediated immunity. Objective: To evaluate the immunomodulatory effects of MSCs supernatant on maturation and function of DCs. Methods: Bone marrow derived m...